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Hydroquinone for Post-inflammatory hyperpigmentation secondary to Acne

Acne Hydroquinone Post-inflammatory hyperpigmentation

Post inflammatory hyperpigmentation (PIH) after acne is commonly seen and can be very disturbing psychologically. These brown spots may persist for months or even years.

Hydroquinone, the skin bleaching agent, is the gold standard for treatment hyperpigmentation including PIH caused by acne.

It can be used in age 13 or older. Hydroquinone is usually started when the acne is resolved. Suggested frequency of application is twice daily for 2 to 6 months. The skin lightening process occurs over 1 to 6 months. If there is no improvement after 2 months, hydroquinone therapy should be discontinued.

Sunscreen with an SPF of at least 15 should be used daily. Hydroquinone can be used safely with concentration not higher than 4% and give the skin a drug holiday (ie Avoid long term and overuse), and as directed by medical practitioner.


Acta Derm Venereol 2012; 92: 232-235

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